The Great Lakes research program is a major part of the activities at CBFS and is led by Watkins and Rudstam. Together with Drs Karatayev and Burlakova from Buffalo State, we continued to monitor all five Great Lakes for zooplankton, benthos and chlorophyll, funded by EPA-Great Lakes National Program Office (GLNPO). CBFS also continued a Great Lakes basin research collaboration with the National Ocean and Atmospheric Administration (NOAA) known as the Cooperative Institute for Great Lakes Research (CIGLR). In 2019, CBFS participated in the Cooperative Science and Monitoring Initiative (CSMI) efforts in Lake Erie. A special issue on Lake Baikal in the Journal of Great Lakes Research was edited by Rudstam and will be published in the first issue of 2020. Holeck and Rudstam continued leading the Lake Ontario lower trophic level biomonitoring program, a cooperation between CBFS, NYDEC, USGS, and USFWS. Two NY Sea Grant projects in Lake Ontario - cisco genetics and tagging Chinook salmon have ended and publications will be forthcoming over the next few years. One cisco project funded by USGS continues and one was completed. Together with researchers from Cornell, Buffalo State, Notre Dame, and the U of Guelph, we are improving the library of genetic barcodes for Great Lake invertebrates. As part of our reporting, we organized four special sessions at IAGLR 2019, and presented at the Great Lakes Fisheries Commissions lake meetings. Finally, three projects that started in 2018 are ongoing, one on the coupling between fish production and lake productivity (Koops et al. GLFC), one on mysid migration (Stockwell et al. GLFC), and one on size spectra analysis (CIGLR).